Evaluation of lutein-loaded PVP nanoparticles in declarative memory of mice

نویسندگان

  • Jéssica T. P. Silva
  • Júlia M. T. Geiss
  • Rafael P. Ineu
  • Fernanda V. Leimann
  • Gustavo P. Guerra
  • Odinei H. Gonçalves
چکیده

Lutein is a xanthophyll carotenoid associated with cognitive improvement (Johnson, 2012). Nevertheless, this compound is very sensitive to external agents. Encapsulation procedures are able to slow down degradation processes and enhance bioavailability. This paper aims the preparation and characterization of lutein-loaded poly(vinyl pirrolidone) nanoparticles and its effect on mice’s declarative memory in object recognition task.

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تاریخ انتشار 2016